Investors are facing unique challenges of heightened market volatility, macro uncertainty and geopolitical crises. Athina Georgopoulou, Vice President at BlackRock and Ben Garland, EMEA Head of Factor Index Products at MSCI discuss how Factors can provide transparency into the drivers of risk and return, helping investors navigate changing market regimes. They also explore the increasing demand to incorporate ESG and Climate principles into Factor portfolios and the associated challenges of designing indexes to accomplish multiple objectives.